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NEW QUESTION: 1
A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. Cannabinoids related
B. H2 receptor antagonist
C. Serotonin 5-HT3 antagonist
D. Blocking dopamine receptors
E. Blockage of prostaglandins
Answer: D
Explanation:
Explanation
B: A variety of drugs have been found to be of some value in the prevention and treatment of vomiting, especially cancer chemotherapy-induced vomiting. With the exception of thioridazine, most of the neuroleptic drugs have antiemetic effects that are mediated by blocking D2 dopaminergic receptors of the chemoreceptor trigger zone of the medulla. Phenothiazines, such as prochlorperazine, were the first drugs shown to be effective antiemetic agents and act by blocking dopamine receptors. They are effective against low to moderately emetogenic chemotherapeutic agents (for example, fluorouracil and doxorubicin). Although increasing the dose improves antiemetic activity, side effects, including hypotension and restlessness, are dose limiting. Other adverse reactions include extrapyramidal symptom and sedation. A: Serotonin 5-HT3 antagonist is incorrect. The specific antagonists of the 5-HT3 receptor, ondansetron and granisetron, selectively block 5-HT3 receptors in the periphery and in the brain (chemoreceptor trigger zone). C:
Cannabinoids related is incorrect. Cannabinoids are marijuana derivatives including dronabinol and nabilone and are effective against moderately emetogenic chemotherapy. However, they are seldom first-line antiemetics because of serious side effects. D: Blockage of prostaglandins is incorrect. Dexamethasone and methylprednisolone used alone are effective against mildly to moderately emetogenic chemotherapy. Their antiemetic mechanism is not known, but it may involve blockade of prostaglandins. E: H2 receptor antagonist is incorrect. Antagonists of histamine H2 receptor block the action of histamine at all H2 receptors; their chief clinical use is as inhibitors of gastric acid secretion.

NEW QUESTION: 2
An IBM Cognos Business Intelligence prospect is leaning towards Tableau because of its strong data visualization capabilities. Which IBM Cognos Business Intelligence capability directly competes with Tableau's data visualization?
A. IBM Cognos Analysis For Microsoft Excel (CAFE)
B. IBM Cognos Workspace Advanced
C. IBM Cognos RAVE charting
D. IBM Cognos Report Studio
Answer: A
Explanation:
Reference:
http://www-03.ibm.com/software/products/en/cognos-analysis-ms-excel

NEW QUESTION: 3
A few transactions have resulted in an error during the Autoinvoice import process. What should use to correct these transactions?
A. File Based Data import
B. Incomplete Transactions
C. ADFDI
D. Manage Transactions
Answer: D

NEW QUESTION: 4
Ein Techniker konfiguriert NAT so, dass das Quellensubnetz von 10.10.0.0/24 in eine von drei Adressen übersetzt wird
192.168.30.1, 192.168.3.2, 192.168.3.3 Welche Konfiguration sollte verwendet werden?

A. Option A.
B. Option C.
C. Option B.
Answer: C